There is an unmistakable urgency about this postseason for Arizona State baseball.

The Sun Devils are likely to lose their top three pitchers and entire starting outfield to graduation and/or pro baseball with no guarantee that the replacements will be good enough or certainly seasoned enough to have them in postseason contention a year from now. For ASU, which last reached the College World Series in 2010, this could be the best chance to return to Omaha in the near future.

But can a No. 2 regional seed with just one sweep all season put together a complete weekend at the right time? The last five weeks suggest otherwise — ASU lost 10 of its last 17 games — but a team with six All-Pac-12 first-teamers, tied for the most with No. 1 NCAA Tournament national seed UCLA, should have enough ability to make a serious run.

Related: ASU baseball returns to Fullerton for sixth postseason

“I think our talent level alone is good enough,” outfielder Trever Allen said. “It’s just that focus and extra effort to do the little things right. That really shows when you’re in the postseason.”

First-year coach Tracy Smith pulled second baseman Andrew Snow on Sunday after the freshman was picked off second base at USC.

“It’s a statement to him certainly but also everybody,” Smith said. “We’ve got to cut down the mental mistakes. We can’t be making the same mistakes from base running to throwing to the wrong base, all that stuff. We’re beyond that.”

ASU (34-21) will play No. 3 seed Clemson (32-27) in the first game of a double-elimination regional in Fullerton, Calif., at 3 p.m. Friday. Game 2 on Saturday, depending on Friday’s result, will be against the winner or loser between No. 1 seed Cal State Fullerton (34-22) and Pepperdine (30-27).

The Sun Devils were eliminated in a regional at Fullerton in 2013 and San Luis Obispo, Calif., in 2014 after being ineligible for postseason in 2012. For pitchers Ryan Kellogg, Brett Lilek, Ryan Burr and Darin Gillies, outfielders Allen, Jake Peevyhouse and Johnny Sewald and first baseman Joey Bielek, it’s now or never for advancing to at least a best-of-three super regional.

“The younger guys especially are playing for them,” sophomore shortstop Colby Woodmansee said. “I would love to be able to give them the opportunity of going places none of us have been.”

Related: ASU baseball opens NCAA play vs. Clemson at CS Fullerton

The winner of the Fullerton regional plays in a super regional against the winner of a regional hosted by No. 3 national seed Louisville (43-16), June 5-8. The regional could put more strain on ASU’s thin pitching staff if it extends to four or five games.

“For us to have a realistic chance, our starters need to give us some quality starts,” Smith said. “That’s first and foremost. If we’re having to stretch the bullpen early (like Friday at USC when Lilek worked just 3.1 innings), that’s going to create some dilemmas for sure.”

Smith will choose between lefties Kellogg (8-2, 3.67 ERA) and Lilek (4-2, 3.29) to start against Clemson with the other pitching Saturday. Lilek started in last year’s regional opener against Pepperdine only to leave in the first inning due to an injury suffered covering first base. The Sun Devils never recovered from that setback, losing two one-run games.

ACC Pitcher of the Year lefty Matthew Crownover (10-2, 1.59) will start for Clemson, 8-3 in its last 11 games, including a sweep of Florida State and a win over Louisville. The Tigers were just 24-24 on May 5 before their late push to a 40th NCAA tourney appearance. ASU is playing in its 38th regional and CS Fullerton in its 37th.

ASU sophomore catcher Brian Serven is expected back after sitting out the USC series due to back pain.

Related: NCAA Division I baseball regionals schedule

“It’s a simple disc issue but not too bad anymore,” Serven said. “I think I’ll be able to do what I normally do without any limitations. It was nice to get a little bit of rest.”

Serven is hitting .301, compared to .261 for backup Zach Cerbo.

Smith said he’ll play matchups and situations in deciding on a designated hitter. Eder Erives, struck in the face by a line drive May 12, could be available to pitch. Jordan Aboites, who started and threw 6.1 innings against Abilene Christian on May 19, also could be a pitching factor, although he also plays infield for defensive purposes.

“It will be all hands on deck,” Smith said. “We will try to win one game at a time. We’re not going to save this guy or that guy. We don’t have that luxury.”

Arizonans in 2015 NCAA Baseball Tournament:

Fullerton NCAA regional

When: Friday-Monday.

Where: Goodwin Field, Fullerton, Calif.

TV: ESPNU (Saturday-Monday night games). Online streaming on ESPN3 (Friday games, Saturday-Sunday day games).

Radio: KDUS-AM (1060) for ASU games.

Friday: No. 2 seed ASU (34-21) vs. No. 3 Clemson (32-27), 3 p.m.; No. 1 Cal State Fullerton (34-22) vs. No. 4 Pepperdine (30-27), 7 p.m.

Saturday: Friday losers, 4 p.m.; Friday winners, 8 p.m.

Sunday: 4/8 p.m.

Monday (if necessary): 8 p.m.

Related: More ASU baseball coverage from Jeff Metcalfe

ASU in NCAA Tournament (since 2000)

2000: Lost Tempe regional.

2001: Lost Fullerton regional.

2002: Lost Mesa regional.

2003: Won Tempe regional, lost Fullerton super regional.

2004: Lost Fullerton regional.

2005: Won Tempe regional, won Fullerton super regional, 3rd College World Series.

2006: Lost Houston regional.

x-2007: Won Tempe regional, won Tempe super regional, 4th CWS.

2008: Won Tempe regional, lost Tempe super regional.

2009: Won Tempe regional, won Tempe super regional, 3rd CWS.

2010: Won Tempe regional, won Tempe super regional, 7th CWS.

2011: Won Tempe regional, lost Austin super regional.

2012: Ineligible.

2013: Lost Fullerton regional.

2014: Lost San Luis Obispo regional.

x-later vacated due to NCAA sanctions.